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目的:比较快速血浆反应素环状卡片试验(RPR)、酶联免疫吸附试验(ELISA)和梅毒螺旋体明胶颗粒凝集试验(TPPA)的检出效果。方法:用三种试验对我院2450例住院患者血清进行检测,不同方法之间比较采用2χ检验。结果:RPR阳性检出率为2.16%,ELISA阳性检出率为2.65%,TPPA阳性检出率为2.61%。RPR与TPPA法比较,差异具有统计学意义。ELISA与TPPA法比较,差异无统计学意义。结论:临床上可采用RPR与ELISA法作为梅毒血清学的过筛试验,对于梅毒的确诊需采用TPPA法。
OBJECTIVE: To compare the detection results of RPR, ELISA and TPPA. Methods: The serum of 2450 hospitalized patients in our hospital was tested by three kinds of tests. The 2χ test was used to compare the different methods. Results: The positive rate of RPR was 2.16%, the positive rate of ELISA was 2.65%, and the positive rate of TPPA was 2.61%. RPR and TPPA method, the difference was statistically significant. ELISA and TPPA method, the difference was not statistically significant. Conclusion: RPR and ELISA can be used clinically as syphilis serological screening test, TPPA method for the diagnosis of syphilis.