病理学目前,对淋巴网细胞瘤(何杰金氏病)的巨网细胞(R-S细胞)有了进一步的认识。巨网细胞分二大类:一类称为诊断性巨网细胞,另一类是巨网细胞的变种。后者又可分为三型:①空隙型巨网细胞(Lacunar type)常在结节硬化型中出现;②多倍性型巨网细胞(Polyploid type)常见于淋巴细胞优势型中;③多形性巨网细胞,多见于淋巴细胞减少型中。在巨网细胞中还发现染色体异常,显示有非整倍性(Aneuploidy)和标记染色体进一步证实恶性肿瘤的特征。近来发现诊断性的巨网细 Pathology Currently, there is a further understanding of giant cell cells (R-S cells) of lymphoblastoma (Hodgkin’s disease). Giant cells are divided into two categories: one is called a diagnostic giant cell, the other is a giant cell variant. The latter can be divided into three types: ① gap type giant cells (Lacunar type) often appear in nodular sclerosis; ② polyploid giant cells (Polyploid type) common in lymphocyte predominance; ③ more Shaped giant cells, more common in lymphopenia. Chromosome abnormalities were also found in giant cells, showing Aneuploidy and marker chromosomes that further confirm malignant features. Recently found that diagnostic giant mesh fine