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目的:观察炙甘草汤加减方与地高辛联用控制持续性房颤的心室率的临床疗效。方法:将100例持续性房颤患者随机分为两组,治疗组(炙甘草汤加减方+地高辛组)55例和对照组(地高辛组)45例。两组均常规给予血管紧张素转换酶抑制剂(ACEI)、利尿、抗凝等对症治疗,疗程12周。结果:治疗组在心室率控制、运动耐量改善方面优于对照组,有统计学意义(P<0.05)。结论:炙甘草汤加减方联合地高辛可有效控制持续性房颤患者的心室率,并提高患者运动耐量。
Objective: To observe the clinical efficacy of Zhigancao Decoction plus digoxin in controlling ventricular rate in patients with persistent atrial fibrillation. Methods: A total of 100 patients with persistent AF were randomly divided into two groups: 55 cases in the treatment group (Zhigancao Decoction + Digoxin) and 45 cases in the control group (Digoxin group). Both groups were routinely given angiotensin converting enzyme inhibitor (ACEI), diuretic, anticoagulation and other symptomatic treatment, the course of 12 weeks. Results: The treatment group was superior to the control group in ventricular rate control and exercise tolerance improvement (P <0.05). Conclusion: Zhigancao Decoction combined with digoxin can effectively control the ventricular rate in patients with persistent atrial fibrillation, and improve patient tolerance.