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目的:探究不同抗菌药物在肝硬化上消化道出血感染治疗中的应用效果。方法:以我院2014年1月到2015年1月期间收治的320例肝硬化上消化道出血感染的患者为研究对象,将其随机分为甲组和乙组。甲组患者使用左氧氟沙星治疗,乙组使用头孢哌酮舒巴坦治疗。对比分析两组患者治疗效果以及不良反应发生率。结果:甲组和乙组治疗总有效率差异不大,不具有统计学意义(P>0.05)。且两组患者用药后不良反应差异不明显,不具有统计学意义(P>0.05)。结论:抗生素抗生素左氧氟沙星和头孢哌酮舒巴坦在治疗肝硬化上消化道出血感染中临床效果相当,均可在临床中推广使用。
Objective: To investigate the effect of different antibacterials on the treatment of upper gastrointestinal bleeding in cirrhosis. Methods: From January 2014 to January 2015 in our hospital, 320 patients with upper gastrointestinal bleeding were enrolled in this study. Patients were randomly divided into two groups. Patients in group A were treated with levofloxacin and in group B were treated with cefoperazone sulbactam. Comparative analysis of two groups of patients and the incidence of adverse reactions. Results: There was no significant difference in the total effective rate between group A and group B, which was not statistically significant (P> 0.05). There were no significant differences in adverse reactions between the two groups after treatment (P> 0.05). Conclusion: The antibiotic antibiotics levofloxacin and cefoperazone sulbactam in the treatment of upper gastrointestinal hemorrhagic infection of liver cirrhosis have similar clinical effects, can be widely used in clinical practice.