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目的了解医院性病门诊和产科门诊孕妇生殖道支原体属感染现状和药物敏感性,分析支原体属耐药性的变化趋势,为临床科学诊断和治疗提供参考依据。方法回顾性分析2011年10月-2012年10月2 186例孕妇支原体属鉴定及12种药物敏感性试验的结果。结果 2 186例孕妇中支原体属培养阳性292例,阳性率为13.36%,其中解脲脲支原体(Uu)感染206例,感染率为9.42%,人支原体(Mh)感染73例,感染率为3.34%,Uu+Mh感染13例,感染率为0.59%;Uu对米诺环素、多西环素、交沙霉素的敏感性最高,分别为99.54%、98.10%、97.70%,对司帕沙星、红霉素、左氧氟沙星的耐药率最高,分别为59.82%、55.25%、47.95%;Mh对米诺环素、多西环素、交沙霉素的敏感性最高,分别为98.84%、97.67%、97.67%,对红霉素、诺氟沙星均100.00%耐药。结论孕妇生殖道中广泛存在支原体属感染,生殖道支原体属对常用抗菌药物的耐药性已相当严重,应引起临床重视。
Objective To understand the prevalence and drug susceptibility of mycoplasma genitalium in STD clinics and obstetric outpatient clinics and to analyze the trends of drug resistance in Mycoplasma and to provide reference for clinical diagnosis and treatment. Methods The results of 2 186 pregnant women with mycoplasma and 12 drug susceptibility tests from October 2011 to October 2012 were retrospectively analyzed. Results The positive rate of mycoplasma in 2 186 pregnant women was 292, with a positive rate of 13.36%. 206 cases were infected with Uu, the infection rate was 9.42%, and 73 cases were infected with Mh. The infection rate was 3.34 %, Uu + Mh infection in 13 cases, the infection rate was 0.59%; Uu on minocycline, doxycycline, josamycin the highest sensitivity were 99.54%, 98.10%, 97.70% The highest rates of resistance were found to be 59.82%, 55.25% and 47.95% respectively for Moxifloxacin, Erythromycin and Levofloxacin. The sensitivity of Mh to minocycline, doxycycline and jasamycin was the highest (98.84% , 97.67% and 97.67%, respectively. The resistance to erythromycin and norfloxacin was 100.00%. Conclusion Mycoplasma genital infection is widespread in the genital tract of pregnant women. Mycoplasma genitalium is very serious resistance to commonly used antimicrobial agents and should be clinically valued.