近年在ＩＣＵ中,出于气管插管和机械通气治疗的需要,以及为了提高危重病例的救治效果,骨骼肌松弛药(肌松药)的应用渐趋增多,而且使用时间多较长(48ｈ),甚至达数周[1～6]。本文就常用肌松药的临床药理和应用、不良反应及其防治等方面的研究进展作一简要介绍。作用机理正常情况 In recent years in the ICU, the need for endotracheal intubation and mechanical ventilation, as well as to improve the treatment of critically ill patients, the use of skeletal muscle relaxants (muscle relaxants) is gradually increasing, and the use of more time (48h) , Even for several weeks [1 ~ 6]. This article commonly used muscle relaxants in clinical pharmacology and application, adverse reactions and prevention and treatment of other aspects of the study made a brief introduction. Mechanism of action normal situation