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Objective To observe the clinical effects of lesionectomies combined with bipolar coagulation of the surrounding cortex (BCSC) on symptomatic epilepsy.Methods The effectiveness of lesionectomies combined with BCSC (71 patients) and of lesionectomies alone (78 patients) were compared in follow-up surveys conducted 2-5 years (average of 37 months) post-operation.Results Treatment in the BCSC group was significantly more effective than in the lesionectomy group (P<0.01). Meanwhile, patients in the BCSC group suffered no permanent post-operative complications.Conclusion Lesionectomy combined with BCSC is a new, effective and safe treatment for symptomatic epilepsy.