粘膜炎是化疗常见的并发症。其疼痛足以影响正常饮食的摄入。目前尚无预防措施,仍然是姑息治疗。为了确定维生素E在短期内治疗化疗引起的粘膜炎是否有效,作者采用了双盲、安慰剂对照的临床试验。 18例癌症患者,其中11例患头颈部癌,5例食管癌,1例肝细胞癌,1例急性骨髓性白血病,先前均接受过化疗,但未接受过放疗和粘膜炎治疗。在其化疗过程中的任何周期中,一经观测到粘膜炎的病变即随机分配以双盲法接受维生素E或安慰剂治疗。对口腔病变局部应用维生素E油1ml(400mg/ml), Mucositis is a common complication of chemotherapy. Its pain is enough to affect normal dietary intake. There is currently no precautionary approach and remains palliative. To determine if vitamin E is effective in treating chemotherapy-induced mucositis in the short term, the authors used a double-blind, placebo-controlled clinical trial. Of the 18 cancer patients, 11 had head and neck cancer, 5 had esophageal cancer, 1 had hepatocellular carcinoma, and 1 had acute myeloid leukemia. They had previously received chemotherapy but did not receive radiation or mucositis treatment. At any stage of the course of chemotherapy, lesions that have been observed for mucositis were randomized to double-blind treatment with either vitamin E or placebo. Oral lesions of the topical application of vitamin E oil 1ml (400mg / ml)