儿童恶性肿瘤多为母细胞瘤,多因发育过程中染色体的编码错误,少部分因受外界损伤所致[1]。其命名反映了肿瘤与原始细胞相关联及其个体发育的不良特征[2]。儿童母细胞瘤来源于未成熟细胞,多因在出生前后分化过程中不能完全转化为成熟组织而恶性增殖,常在5岁前发病[1]。神经母细胞瘤、视网膜母细胞瘤、肾母细胞瘤和肝母细胞瘤是儿童 Most of children with malignant tumors are blastocysts, mostly due to the coding errors of chromosomes during development, and a small number of them are due to external damage [1]. Its nomenclature reflects the adverse characteristics of the tumor associated with the primitive cell and its individual development [2]. Childhood blastoma from immature cells, mostly because of the process of differentiation can not be completely transformed into mature tissue before and after malignant proliferation, often in the 5-year-old onset [1]. Neuroblastoma, retinoblastoma, Wilms tumor and hepatoblastoma are children