原始巨核细胞白血病的诊断仍然根据细胞形态大小,电镜的所见和对巨核细胞系有特异性的血小板过氧化物酶。患者常由于血小板功能异常而出血。作者报告1例原始巨核细胞白血病患者的血小板功能特点。患者男性,52岁。β-地中海贫血携带者,因双侧颌下及颈后淋巴结肝脾肿大,伴有不规则发热,体重减轻,出汗,虚弱;无出血倾向。入院时检查:血红蛋白9,5g,白细胞5,600,血小板19.5万且有形态学异常,包括巨血小板和聚集血小板。血沉增快,多克隆高丙种球蛋白血症(2.43g％)。锁骨上淋巴结活检 The diagnosis of primary megakaryoblastic leukemia is still based on cell size, electron microscopy and megakaryocytic cell line is specific for platelet peroxidase. Patients often have bleeding due to abnormal platelet function. The authors report the platelet function of a patient with primary megakaryoblastic leukemia. Male patient, 52 years old. β-thalassemia carriers, due to bilateral submandibular and cervical lymph nodes of hepatosplenomegaly, accompanied by irregular fever, weight loss, sweating, weakness; no bleeding tendency. Admission examination: 9,5 g hemoglobin, 5,600 leukocytes, 195,000 platelets and morphological abnormalities, including giant platelets and platelet aggregation. Rapid erythrocyte sedimentation rate, polyclonal hypergammaglobulinemia (2.43g%). Supraclavicular lymph node biopsy