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目的探讨喘定(二羟丙茶碱注射液)与吗啡或甲泼尼龙联用缓解晚期肿瘤呼吸困难的效果。方法 300例晚期肿瘤呼吸困难患者,随机分为吗啡组和甲泼尼龙组,各150例。吗啡组患者给予喘定联合吗啡治疗,甲泼尼龙组给予喘定联合甲泼尼龙治疗。对比治疗效果。结果治疗后,吗啡组视觉模拟评分法(VAS)评分(13.22±10.31)mm低于甲泼尼龙组(24.36±16.54)mm(P<0.05)。吗啡组治疗有效率86.67%高于甲泼尼龙组66.67%(χ2=16.770,P<0.05)。结论喘定与吗啡、喘定与甲泼尼龙用于治疗晚期肿瘤呼吸困难患者均有效,且喘定与吗啡的疗效显著高于喘定与甲泼尼龙的疗效,能保证有效缓解,值得在治疗上使用。
Objective To investigate the effect of omeprazole (dipyridamol injection) combined with morphine or methylprednisolone in relieving dyspnea of advanced tumors. Methods 300 patients with advanced dyspnea who were randomly divided into morphine group and methylprednisolone group (150 cases each). Patients in morphine group were treated with asthma combined with morphine, while those in methylprednisolone group were treated with asthma combined with methylprednisolone. Compare the treatment effect. Results After the treatment, the visual analog scale (VAS) score of morphine group (13.22 ± 10.31) mm was lower than that of methylprednisolone group (24.36 ± 16.54) mm (P <0.05). The effective rate of morphine group was 86.67% higher than that of methylprednisolone group (66.67%, χ2 = 16.770, P <0.05). CONCLUSIONS: Both asthma and morphine, asthma and methylprednisolone are effective in the treatment of patients with advanced stage dyspnea, and the efficacy of asthma and morphine is significantly higher than that of asthma and methylprednisolone, which can be effectively relieved and worthy of treatment Use on.