目的:比较不同产地、不同炮制品知母中主要药效成分菝葜皂苷元含量。方法:以菝葜皂苷元含量为指标对不同产地、不同炮制品知母进行含量测定。结果:各产地知母中菝葜皂苷元的含量差别较大,经盐炙后菝葜皂苷元含量无明显差异。结论:山西产的知母中菝葜皂苷元含量最高;以菝葜皂苷元为主要治疗成分时,使用生品、盐炙品均可。 OBJECTIVE: To compare the content of saponins in the main effective components of Rhizoma Anemarrhenae from different producing areas and different processed products. Methods: The contents of Anemarrhena with different origins and different processed products were determined with the content of saponins. Results: The content of saponin in Zhimu of different producing areas differed greatly. There was no significant difference in the content of saponins after salting. Conclusion: The content of triterpenoid saponins in Anemarrhenae of Shanxi Province is the highest. When triterpene saponin is used as the main therapeutic ingredient, the use of raw materials and salt glycosides can be used.