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临床上合并子宫肌瘤绝经后妇女常需用激素替代疗法(HRT)。一般认为HRT常引起肌瘤再生长及相关症状复发。随机观察两种HRT方法对绝经后子宫肌瘤的影响。 对象为38例绝经前因肌瘤引起月经过多已接受治疗者。进入研究前停用GnRH拮抗剂6个月以上。患者年龄46~52岁。闭经至少6月。开始HRT治疗前1月FSH≥50IU/L。同时经腹部及阴道超声检查发现1个或多个子宫肌瘤,至少有1个
Clinically combined uterine fibroids postmenopausal women often need hormone replacement therapy (HRT). Generally believed that HRT often cause fibroids regrowth and related symptoms recurrence. Randomly observe the effects of two HRT methods on postmenopausal uterine fibroids. Subjects for the 38 cases of premenopausal menarche caused by fibroids have been treated. GnRH antagonists were stopped for more than 6 months before entering the study. Patients aged 46 to 52 years old. Amenorrhea for at least 6 months. FSH≥50IU / L before the start of HRT treatment in January. At the same time by abdominal and vaginal ultrasound examination found one or more uterine fibroids, at least one