论文部分内容阅读
作者为了探讨熊去氧胆酸(ursodeoxy cholicacid,UDCA)对药物性迁延性肝内胆汁郁积病者的效果,进而探讨 UDCA 对伴随强直性肌营养不良症所出现的胆道系统酶类的影响,共对6例患者进行了研究。其中4例患者中3例有黄疸,1例无黄疸但碱性磷酸酶(ALP)高值,另2例为强直性肌营养不良伴胆道系统酶类异常。所有病例服 UDCA 600mg/d,对3例黄疸患者都起到黄疸减退的作用,其中1例因安乃近引起药物性肝内胆汁郁积,曾给强的松40mg/d,效果不佳,总胆红素值增高至28.9mg/
To explore the effect of ursodeoxycholic acid (UDCA) on patients with drug-induced intrahepatic cholestasis and to explore the effect of UDCA on biliary system enzymes associated with myotonic dystrophy Six patients were studied. Of the 4 patients, 3 had jaundice, 1 had no jaundice but high ALP, and 2 had ankylosing muscular dystrophy with abnormal biliary system enzymes. All cases of UDCA 600mg / d, jaundice in 3 patients have played a role in the decline of jaundice, of which 1 cases of drug-induced intrahepatic cholestasis caused by analgin, had given prednisone 40mg / d, the effect is not good, the total Bilirubin value increased to 28.9mg /