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本文主要介绍有关白细胞介素—1在胰岛素依赖性糖尿病(IDDM)发病机制中作用的新学说。该学说认为:IDDM胰岛β细胞的破坏作用为非MHC限制性,但同MHC基因的调控和胰岛β细胞的特异性有关。
This article describes a new doctrine of interleukin-1 in the pathogenesis of insulin-dependent diabetes mellitus (IDDM). The theory is that: the destruction of IDDM pancreatic β-cells is non-MHC-restricted but related to the regulation of MHC genes and the specificity of pancreatic β-cells.