女,58岁,护士,住院号29557。因烦渴易饥5年,四肢皮肤感觉异常2月,于1986年3月17日入院。患者5年前出现烦渴易饥症状,经检查发现血糖200mg％,尿糖(+++),确诊为糖尿病。患者自行控制饮食,用优降糖2.5mg,每日一次,血糖控制在130～200mg％之间,尿糖(-)。近2月来逐渐出现四肢麻木、刺痛、时有触电样感觉,怕接触热物,冷水浸泡肢体可减轻疼痛,四肢乏力,时有肌肉抽动,活动障碍,行走困难。体查:体温36.4℃、脉搏78次,呼吸20次,血压100/60。发育正常,营养中等,神清,合作。头颅五官无异常,心肺(-),肝脾不大。神经系纹检查:颅神经(-),右上、下肢肌力Ⅳ°,左上、下肢肌力Ⅴ°,右上、下肢肌张力稍高。双上肢掌横纹以下、双下肢踝关节以下皮肤感觉过敏,四肢深反 Female, 58 years old, nurse, hospital number 29557. Due to thirsty easily hungry for 5 years, limbs and skin abnormalities in February, on March 17, 1986 admission. 5 years ago, patients with symptoms of irritability thirst, after examination revealed that blood sugar 200mg%, urine sugar (+++), diagnosed with diabetes. Patients to control their own diet, with glyburide 2.5mg, once daily, blood sugar control between 130 ~ 200mg%, urine sugar (-). Nearly two months gradually numbness, tingling, electric shock-like feeling, fear of exposure to heat, cold water immersion limbs can reduce pain, limb weakness, sometimes muscle twitching, mobility disorders, walking difficulties. Physical examination: body temperature 36.4 ℃, pulse 78 times, breathing 20 times, blood pressure 100/60. Normal development, nutrition is medium, clear, cooperation. No abnormalities in the head and facial features, heart and lung (-), liver and spleen is not. Nervous system examination: cranial nerve (-), right upper quadrant muscle strength Ⅳ °, upper left and lower limb muscle strength Ⅴ °, upper right and lower limb muscle tone slightly higher. Double upper limb below the horizontal stripes, lower extremity ankle below the skin sensitization, limb deep