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近年来,对因子Ⅷ相关抗原(简称ⅧR:Ag)的研究有了很大的进展。ⅧR:Ag抗血清已初步应用于临床。它除用于鉴别血管性假血友病与血友病甲外,还可作为某些疾病反映高凝状态的一项有用指标,并对某些疾病的发生、病理生理以及对其颅后的判断等也具有一定的意义。我们曾对494例各种贫血与肿瘤、特发性血小板减少性紫癜、心肌梗塞、病毒性肝炎、肺结核等患者以及妊娠妇女测定其血浆ⅧR:Ag,试图从中探讨其生理或病理改变及其临床意义。现将结果总结如下。
In recent years, the research on factor Ⅷ related antigen (ⅧR: Ag) has made great progress. Ⅷ R: Ag antiserum has been initially applied in clinical practice. In addition to identifying von Willebrand disease and hemophilia A, it can also be used as a useful indicator of hypercoagulability for certain diseases and for the development of certain diseases, their pathophysiology, and their post-cranial Judgment also has some significance. We examined plasma Ⅷ R: Ag in 494 patients with anemia and neoplasms, idiopathic thrombocytopenic purpura, myocardial infarction, viral hepatitis, tuberculosis, and in pregnant women in an attempt to explore their physiological or pathological changes and their clinical implications significance. The results are summarized below.