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1例46岁男性患者,因下肢皮肤湿疹服用某诊所自制中药丸(每粒约含21mg轻粉)1粒,2次/d,共服用13粒。第7天患者出现头晕、胸闷、口腔溃疡伴发热、周身疼痛,且症状逐渐加重遂入院。查体:T37.2℃,面部及躯干部皮肤可见充血性红斑,压之褪色;口腔黏膜充血,齿龈红肿。实验室检查:血汞0.029mg/L,尿汞39.565μmol/molCr;ALT61U/L,AST28U/L,BUN7.42mmol/L,SCr67.0μmol/L;血β2-微球蛋白1549.20ng/ml;尿β2-微球蛋白167.0ng/ml。给予二巯基丙磺酸钠治疗,患者症状好转,尿汞趋于正常,复查示肝功能及血、尿β2-微球蛋白水平恢复正常。
A 46-year-old man with pelvic floor eczema taken a clinic made of Chinese medicine pills (each containing about 21mg light powder) 1, 2 times / d, taking a total of 13. Day 7 patients with dizziness, chest tightness, oral ulcers with fever, whole body pain, and symptoms gradually increased then hospitalized. Physical examination: T37.2 ℃, facial and torso skin visible congestion of erythema, pressure fade; oral mucosal hyperemia, inflamed gums. Laboratory tests: blood mercury 0.029mg / L, urine mercury 39.565μmol / molCr; ALT61U / L, AST28U / L, BUN7.42mmol / L, SCr67.0μmol / L; blood β2-microglobulin 1549.20ng / β2-microglobulin 167.0 ng / ml. Give mercaptopropionate sodium treatment, the patient’s symptoms improved, urine mercury tends to normal, check liver function and blood, urine β2-microglobulin levels returned to normal.