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目的探析干扰素栓联合阿奇霉素治疗衣原体、支原体性宫颈炎的临床治疗效果。方法选取2014年6月至2015年6月就诊的衣原体、支原体性宫颈炎患者60例,随机分为两组,每组各30例,分别为观察组和对照组。对照组给予患者阿奇霉素进行治疗,观察组在对照组基础上同时使用干扰素栓,两组患者均持续用药2周。对比两组患者的临床治疗有效率、复发率、聚合酶链式反应(Polymerase Chain Reaction,PCR)检测转阴时间。结果观察组的治疗有效率93.3%,对照组有效率70.0%,差异具有统计学意义(P<0.05)。观察组患者PCR检测转阴时间为(6.2±1.6)d,明显低于对照组的(9.8±2.3)d,差异具有统计学意义(P<0.05),对照组患者复发8例(26.7%),高于观察组的3例(10.0%),两组对比,差异具有统计学意义(χ2=2.783,P<0.05)。结论采用干扰素联合阿奇霉素治疗衣原体、支原体性宫颈炎有明显效果,能显著改善患者衣原体及支原体的阳性症状,降低治疗后的复发率,可作为有效治疗方案推广。
Objective To investigate the clinical efficacy of interferon suppository combined with azithromycin in the treatment of chlamydia and mycoplasma cervicitis. Methods Sixty patients with chlamydial and mycoplasmal cervicitis were selected from June 2014 to June 2015, and randomly divided into two groups, 30 cases in each group, which were observation group and control group respectively. Patients in the control group were treated with azithromycin, and the observation group was given interferon suppository on the basis of the control group. The patients in both groups continued to receive medication for 2 weeks. The clinical efficacies, recurrence rates, and Polymerase Chain Reaction (PCR) were compared between the two groups. Results The effective rate of treatment was 93.3% in observation group and 70.0% in control group, the difference was statistically significant (P <0.05). In the observation group, the time for PCR detection was (6.2 ± 1.6) d, which was significantly lower than that in the control group (9.8 ± 2.3) d, with statistical significance (P <0.05). In the control group, 8 patients (26.7% , Higher than that of the observation group (10.0%). There was significant difference between the two groups (χ2 = 2.783, P <0.05). Conclusion Interferon combined azithromycin treatment of chlamydia, mycoplasma cervicitis has obvious effect, can significantly improve the positive symptoms of patients with chlamydia and mycoplasma and reduce the recurrence rate after treatment, can be used as an effective treatment to promote.