瞳孔对光反应与近点(调节)反应分离现象在无视力丧失的情况下临床上见于许多疾病:神经梅毒、Adie氏强直瞳孔、慢性青年性糖尿病、大脑导水管综合征(如松果体瘤)、第3神经变性迷生、胶元性血管病、感染后脑炎、多发性硬化症、眼外伤、眼带状疱疹、垂体瘤、肌营养不良、类淀粉样变性症、全植物神经功能失调、Riley-Day家族性植物神经功能失调、Miller Fisher综合征、家族性感觉性神经病以及Charcot-Marie-Tooth氏病。由于瞳孔的近点反应不常注意,所以常常被忽略。作者报告1例,男性51岁患糖尿病10年,急性发生右眶部不适及复视。检查发现右侧动眼神经麻痹,右侧瞳孔大于 Pupillary photoreaction and near-point (regulatory) response to the phenomenon of the absence of loss of vision clinically seen in many diseases: neurosyphilis, Adit’s ankylosis pupil, chronic youth diabetes, cerebral aqueduct syndrome (such as pineal tumor ), Neurodegenerative neurodegeneration 3, mesogenic vasculopathy, post-infection encephalitis, multiple sclerosis, ocular trauma, ocular herpes zoster, pituitary tumor, muscular dystrophy, amyloidosis-like, full autonomic function Dysregulation, Riley-Day familial autonomic dysfunction, Miller Fisher syndrome, familial sensory neuropathy, and Charcot-Marie-Tooth’s disease. Often overlooked because the pupil’s near-point reaction is less noticeable. The authors report 1 case of male 51-year-old suffering from diabetes for 10 years, acute right orbital discomfort and diplopia. Examination found that the right oculomotor nerve paralysis, the right pupil than