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人类基因治疗的成功给眼科工作者带来了希望,从人类基因治疗的发展历史可以看到眼科遗传病基因治疗的美好前景,基因治疗的总体思想和策略的日趋成熟推动着眼科基因治疗的发展,从首次发现外源性 RB_1基因导入视网膜母细胞瘤细胞可改变其致癌特性到近期人类用转基因技术治疗视网膜变性和视网膜慢性变性均展示了实施眼科基因治疗的可行性。
The success of human gene therapy has brought hope to ophthalmologists. From the history of human gene therapy, we can see the bright future of gene therapy for ophthalmic genetic diseases. The general idea and tactics of gene therapy are driving the development of ophthalmic gene therapy , From the first discovery of exogenous RB_1 gene into retinoblastoma cells can change its oncogenic properties to the recent human use of transgenic technology for the treatment of retinal degeneration and chronic retinal degeneration have demonstrated the feasibility of implementing ophthalmic gene therapy.