药物释放概念已引起人们广泛兴趣,多品种释放系统现已投入市场。这些制剂目的在药物通过胃肠道时,持续地将其释放,使能在长时间内恒定血浆药物浓度,从而可能减少副作用。理想的缓慢释放制剂取决于活性物质的溶解速率。许多因素,例如机械影响、酶、粘滞度,表面张力,pH,盐浓 The concept of drug release has attracted widespread interest and multi-species delivery systems are now available. The purpose of these formulations is to continually release the drug as it passes through the gastrointestinal tract, allowing for constant plasma drug concentration over an extended period of time, potentially reducing side effects. The ideal slow release formulation depends on the rate of dissolution of the active substance. Many factors, such as mechanical influence, enzyme, viscosity, surface tension, pH, salt concentration