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前列腺素是具有广泛生理活性的激素,具有多种生理功能:(一)生殖系统——可引起子宫收缩,能对足月妊娠引产,也能防止或减少受孕,作为一种事后避孕药。(二)心血管系统——(1)能降低外周血管阻力,降低血压,临床上用于治疗肾源性高血压,效果较佳。(2)用于冠心病,它可能降低冠脉的阻力,增加其血流量,并能抑制血小板凝集,降低血中游离脂肪酸,故可用于冠心病及动脉粥样硬化的防治。(三)呼吸系统——对支气管有明显的舒张作用,并能促使粘痰咳出,故可用于治疗支气管哮喘。(四)消化系统——前列腺素对胃肠平滑肌的兴奋作用较强,动物实验证明:可抑制
Prostaglandins are hormones with a wide range of physiological activities and have a variety of physiological functions: (a) The reproductive system - can cause uterine contractions, can induce labor in term pregnancy, and can also prevent or reduce pregnancy, as a type of postmortem pill. (B) Cardiovascular system - (1) can reduce peripheral vascular resistance, lower blood pressure, clinically used for the treatment of nephrogenic hypertension, the effect is better. (2) for coronary heart disease, it may reduce coronary resistance, increase blood flow, and can inhibit platelet aggregation, reduce blood free fatty acids, it can be used for the prevention and treatment of coronary heart disease and atherosclerosis. (c) Respiratory system - There is a clear diastolic effect on the bronchus, and can promote stickiness and expectoration, so it can be used to treat bronchial asthma. (D) The digestive system - prostaglandins on the gastrointestinal smooth muscle excitatory effect is stronger, animal experiments show that: can be suppressed