本文用电磁流量计法测定头痛神效丹对狗脑血流量及脑血管阻力的药理效应。结果表明,0.48g/kg头痛神效丹能增加脑血流量的峰值平均达430.95±71.55ml/100g/min,比给药前增加27.01%。0.96g/kg时脑血流量峰值平均达491.43±81.89ml/100g/min,比给药前增加44.84%。静脉推入本品后,脑血管阻力均降低,作用强度随药物剂量增加而加强。 This article uses electromagnetic flowmeter method to measure the pharmacological effects of headache and Xiaodan on cerebral blood flow and cerebrovascular resistance in dogs. The results showed that the peak value of 0.48g/kg headache ShenShandan increased cerebral blood flow averaged 430.95±71.55ml/100g/min, which was 27.01% higher than before administration. The peak value of cerebral blood flow at 0.96g/kg was 491.43±81.89ml/100g/min, which was 44.84% higher than before administration. After intravenous administration of this product, the cerebral vascular resistance was reduced, and the effect strength was enhanced with the increase of the drug dose.