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目的:评价离心甩片法检测脑脊液抗酸杆菌(AFB)的应用价值。方法:应用离心甩片法和常规方法对167例结核性脑膜炎患者(结脑组)和68例非结脑患者(对照组)的脑脊液检测AFB,比较两种方法阳性率的差别。结果:结脑组AFB的阳性率,离心甩片法为62.9%、常规方法为12.6%,两种方法的阳性率有统计学差异(P<0.01)。68例对照组的脑脊液均未查出AFB阳性结果。结论:离心甩片法检测脑脊液AFB的特异性与常规方法一致而阳性率远高于常规方法,可替代常规方法开展应用。
Objective: To evaluate the value of centrifugation rejection in the detection of acid-fast bacilli in cerebrospinal fluid (AFB). Methods: The cerebrospinal fluid of 167 patients with tuberculous meningitis (tuberculous meningitis group) and 68 patients with non-tuberculous meningitis (control group) were detected by centrifugation rejection and routine methods. The difference of the positive rate of the two methods was compared. Results: The positive rate of AFB in the tuberculin group was 62.9% by centrifugation and 12.6% by conventional method. There was a significant difference between the two methods (P <0.01). 68 patients in the control group did not detect AFB positive results of cerebrospinal fluid. CONCLUSION: The specificity of centrifugation rejection method in detecting cerebrospinal fluid AFB is consistent with the conventional method, but the positive rate is much higher than the conventional method, which can replace the conventional method.