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摄入过量含碘药物与化学品引起的甲亢称之为碘甲亢。1921年Coindet首先报告了碘化物治疗地方性甲减时引起了甲亢,此后世界各地不断有类似报告。1972年Vagenakis等首先报告了非缺碘地区碘化物引起甲亢。一、甲状腺与碘代谢: 碘是合成甲状腺激素的必需原料。正常人体含碘约50毫克,20%分布于甲状腺,50%分布于肌肉,10%分布于皮肤,骨骼约占6%,重量仅有20
Hyperthyroidism caused by excessive intake of iodine-containing drugs and chemicals is called iodine hyperthyroidism. Coindet first reported in 1921 that iodide treatment caused hyperthyroidism when endemic hypothyroidism was treated, and subsequent reports from around the world continued. In 1972, Vagenakis et al. First reported hyperthyroidism caused by iodide in non-iodine-deficient areas. First, the thyroid and iodine metabolism: Iodine is an essential raw material for the synthesis of thyroid hormones. Normal human iodine about 50 mg, 20% distributed in the thyroid gland, 50% distributed in the muscle, 10% distributed in the skin, bones accounted for about 6%, weighing only 20