论文部分内容阅读
目的分析上海市四家社区卫生服务中心门诊抗菌药物使用情况。方法选取2014—2015年上海市四家社区卫生服务中心门诊处方552.66万张,对处方中的药名及剂型、类别、销售金额、用药频度(DDDs)、日均费用(DDC)予以全面分析。结果含抗菌药物总处方为37.16万张,占总处方的6.72%(37.16/552.66);2014—2015年各级抗菌药物DDDs差异不大,维持基本平稳状态;2014、2015年头孢菌素类使用金额占抗菌药物总金额分别为70.20%、68.76%,第2位、第3位分别为大环内酯类及喹诺酮类,DDDs排序依次为头孢菌素类、喹诺酮类、大环内酯类;2014—2015年前10位药品的金额占抗菌药物金额分别为92.69%、88.72%,头孢菌素类有6种;2014年头孢替安注射剂型、头孢克洛口服剂型、头孢呋辛口服剂型分别位于前3位,2015年依次为头孢替安注射剂型、头孢克洛口服剂型、头孢丙烯口服剂型;2014—2015年DDDs排序前3位药品分别为左氧氟沙星口服剂、头孢呋辛口服剂型、甲硝唑口服剂型,日均费用最低的是甲硝唑口服剂型为0.61元;2014—2015年抗菌药物静脉给药使用金额为528.74万元,占抗菌药物总销售金额的35.09%(528.74/1506.68),抗菌药物静脉给药处方占抗菌药物处方的4.96%。结论本市四家社区卫生服务中心门诊抗菌药物的使用基本合理,但需进一步提高抗菌药物临床应用水平。
Objective To analyze the use of antibacterials in outpatient departments of four community health service centers in Shanghai. Methods A total of 5,526,600 outpatient prescriptions were collected from four community health service centers in Shanghai from 2014 to 2015. The prescriptions were analyzed comprehensively in terms of drug names, dosage forms, sales volume, DDDs, and daily cost (DDC) . Results The total number of prescriptions containing antimicrobial drugs was 371,600, accounting for 6.72% (37.16 / 552.66) of the total prescription. The DDDs of antimicrobial drugs at all levels varied slightly from 2014 to 2015, maintaining a basically steady state. In 2014 and 2015, the use of cephalosporins The total amount of antimicrobial drugs accounted for 70.20% and 68.76% respectively. The second and third place were macrolides and quinolones, the order of DDDs were cephalosporins, quinolones and macrolides; The amount of the top 10 drugs in 2014-2015 accounted for 92.69% and 88.72% of the total amount of antibacterial drugs and 6 cephalosporins respectively. In 2014, cefotiam injection, cefaclor and cefuroxime were administered separately The top 3 drugs were cefotiam injection, cefaclor oral and cefprozil oral preparations in 2015. The top three drugs in DDDs distribution in 2014-2015 were oral levofloxacin, oral cefuroxime, Azole oral dosage forms, the lowest daily average cost of metronidazole oral dosage form was 0.61 yuan; 2014-2015 antimicrobial drug intravenous use amount of 528.74 million yuan, accounting for 35.09% (528.74 / 1506.68) of the total sales of antimicrobial drugs, Antimicrobial drugs are administered intravenously Parties accounted for 4.96% of antibiotics prescribed. Conclusion The use of antibacterials in outpatient clinics in four community health service centers in the city is basically reasonable, but the clinical application of antibacterials needs to be further improved.