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Graves病甲亢患者甲状腺淋巴细胞浸润程度与血清甲状腺抗体有关,抗体阳性者在甲状腺次全切术后容易发生甲状腺机能减退。另外,约20%的Graves病甲亢患者在停用抗甲状腺药物治疗后发生甲减。这些病人甲状腺组织的破坏被认为是由于自身免疫机制或/和存在TSH阻断抗体。然而有些研究发现,Graves病血清MCHA(抗甲状腺微粒体抗体)滴度较高者复发率较高。为进一步研究
The degree of thyroid lymphocyte infiltration in patients with Graves’ disease is related to serum thyroid antibody. The antibody positive patients are prone to hypothyroidism after subtotal thyroidectomy. In addition, about 20% of hyperthyroid patients with Graves’ disease develop hypothyroidism after antithyroid drugs are discontinued. Thyroid tissue destruction in these patients is thought to be due to an autoimmune mechanism or / and the presence of TSH blocking antibodies. However, some studies have found that Graves disease serum MCHA (anti-thyroid microsomal antibody) higher titers have a higher recurrence rate. For further research