论文部分内容阅读
Sandostatin(SMS 201—995)为一长效生长抑素(SS)类似物,它抑制生长激素(GH)分泌,经常可改善肢端肥大症(脑下垂体瘤所致产生过剩GH引起的临床及生化表现)。但它对肿瘤大小及由于肿瘤向蝶鞍外扩散引起的神经科症状的疗效则不明显。曾有报告在治疗中肿瘤大小不变或稍有缩小。 作者近期治疗了61例由于脑下垂体腺瘤鞍上扩展引起的肢端肥大症有视力症状的病人。因以前曾用SS类似物治过6例肢端肥大症患者,肿瘤体积缩小10～33%,故设想单独使用此种药物以减低视
Sandostatin (SMS 201-995) is a long-acting somatostatin (SS) analog which inhibits the growth hormone (GH) secretion and often improves acromegaly (resulting from pituitary tumor-causing excess GH Biochemical performance). However, its effect on tumor size and neurological symptoms caused by tumor spread to the sella is not obvious. Tumor size has been reported to have remained unchanged or slightly diminished during treatment. The authors recently treated 61 patients with acromegaly who developed visual acuity due to suprasellar pituitary adenoma expansion. Because previously used SS analogs over 6 cases of acromegaly patients, tumor size reduced by 10 to 33%, it is envisaged that the use of such drugs alone to reduce visual acuity