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选择经纤维胃镜确诊为活动期消化性溃疡,活检证实均伴有不同程度的活动性慢性浅表性胃炎,快速尿素酶试验和组织切片嗜银染色证实幽门螺旋菌阳性的88例,随机分治疗组60例,对照组28例,分别采用雷尼替丁加得乐冲剂或单用雷尼替丁口服,连续服药4周为一疗程,治疗结束后由同一医师行胃镜复查,观察结果:治疗组消化性溃疡愈合率96.6％;HP清除率85％;胃粘膜炎症好转率56.6％;均显著高于对照组。说明西药合用对HP阴性消化性溃疡的疗效明显优于单用雷尼替丁组。
Eighty-eight patients with Helicobacter pylori positive were confirmed by biopsy confirmed by biopsy and biopsy with varying degrees of active chronic superficial gastritis, rapid urease test and histological section silver staining. 60 patients in the control group and 28 patients in the control group were treated with ranitidine plus dexamethasone alone or ranitidine alone for 4 weeks. After the treatment, the same physician underwent gastroscopy and the results were as follows: The healing rate of peptic ulcer was 96.6%; HP clearance rate was 85%; gastric mucosal inflammation improvement rate was 56.6%; all were significantly higher than the control group. Description of Western medicine on the efficacy of HP-negative peptic ulcer was significantly better than ranitidine alone group.