爱维治(Actovegin)系小牛血清提取物,是小分子量(分子量<5000道尔顿)的肽、核苷酸和寡糖类物质。它不含蛋白质、致热原和任何传播性感染因子。该药在欧洲应用于治疗神经系统疾病已20多年,并在日本、东南亚等许多国家广泛应用,我国上海、北京现已用于临床,反应良好。现将该药的主要药理作用、机制、临床应用及药效综述如下。1 主要药理作用及机制1.1 促进缺氧细胞对氧与葡萄糖的摄取和利用爱维治能直接改善细胞能量代谢,使细胞摄氧增加,促进血葡萄糖进入细胞内,增加能量合成。这一作用对缺血、缺氧细胞尤为显著,并能显著延长 Actovegin is a bovine serum-derived extract that is a peptide, nucleotide and oligosaccharide of low molecular weight (<5000 daltons). It contains no protein, pyrogen and any infectious agents. The drug used in Europe for the treatment of nervous system diseases for more than 20 years, and widely used in many countries such as Japan, Southeast Asia, Shanghai, Beijing, China is now used clinically, responded well. Now the main pharmacological effects of the drug, mechanism, clinical application and efficacy are summarized below. 1 The main pharmacological effects and mechanisms 1.1 Promote the hypoxic cells of oxygen and glucose uptake and utilization of Viagra can directly improve cell energy metabolism, oxygen up cells, promote blood glucose into the cell, increase energy synthesis. This effect on ischemia, hypoxic cells is particularly significant, and can be significantly prolonged