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脊索瘤(Chordoma)是一罕见恶性肿瘤,起源于残余的胚胎脊索,发生在脊柱轴线上神经与躯干骨交界处附近。本病约50％发生于骶尾部,35％在蝶骨底区,15％在椎体~2。多采用手术切除。本瘤生长缓慢、病程长,多有局部疼性压迫症状。Cummings(1983)等报告自1958年以来收治的25例脊索瘤病人中,年龄在23—77岁之间,中数年龄53岁。肿瘤位于颅底者10例,皆有颅神经受累,有的继发肿块阻塞鼻咽。其中位于蝶枕骨9例,颞岩骨1例。自出现症状到诊断为期1月到4年,中数12月。位于骶尾部12例皆有不同程度的局部疼痛及肿块,伴有尿道和肛门括约肌的功能障碍。位于腰椎者2例,颈椎者1例。
Chordoma is a rare malignant tumor that originates from the residual embryo chordate that occurs near the junction of the nerve and the trunk bone on the spine axis. About 50% of the disease occurs in the sacrococcygeal, 35% in the sphenoid area, 15% in the vertebral body ~ 2. Use surgical resection. The slow growth of the tumor, longer duration, more local symptoms of oppression. Cummings (1983) and other reports of 25 cases of chordoma admitted since 1958, aged 23-77 years, the median age of 53 years. Tumors located in the skull base in 10 cases, all have cranial nerve involvement, and some secondary mass blocking the nasopharynx. Among them, 9 cases were located in the butterfly sphenoid bone and 1 case was petrous bone. Since the onset of symptoms to the diagnosis period of 1 to 4 years, the number of December. In the sacrococcygeal 12 cases have varying degrees of local pain and mass, accompanied by urethral and anal sphincter dysfunction. 2 cases located in lumbar spine, 1 case of cervical spine.