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近日,中科院强磁场科学中心双聘研究员陈乾旺、中科大生命科学学院郭振副教授、安徽医科大学王海宝副主任医师三课题组合作,利用肿瘤细胞内环境的调控,发展了具有pH响应性的多功能药物载体,它能够将疏水药物青蒿素输送到肿瘤细胞内,同时释放出可作为青蒿素抗癌的诱导剂的Fe2+,从而大大提高了抗癌药效。博士生陈健制备出一种具有多孔结构的Fe3O4@C/Ag@mSiO2纳米粒子。利用该材料的高比表面积,实现了高的药物装
Recently, Chen Hong-wang, a dual-employed researcher at the Strong Magnetic Field Science Center of the Chinese Academy of Sciences, Associate Professor Guo Zhen of the School of Life Science at the Chinese University of Science and Technology and Deputy Chief Physician Wang Haibao of Anhui Medical University worked together to develop a pH-responsive multifunctional The drug carrier, which can deliver hydrophobic drug artemisinin into tumor cells and release Fe2 +, which can act as an inducer of artemisinin anti-cancer, greatly enhances anti-cancer efficacy. Ph.D. Chen Jian prepared a porous structure of Fe3O4 @ C / Ag @ mSiO2 nanoparticles. Utilizing the high specific surface area of the material, high drug loading is achieved