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以对幼雌小鼠的子宫增重作用及对去卵巢小鼠的雌性活性作用持续时间为指标,对雌二醇、戊酸雌二醇、乙炔雌二醇的聚乙二醇高分子化合物雌性活性的量效及时效关系作了初步测定,结果表明,在本实验条件下,雌二醇、戊酸雌二醇、乙炔雌二醇的聚乙二醇高分子化合物与原母体化合物比较其雌激素活性较弱,作用持续时间未见延长。
Based on the effect of uterus weight gain and the duration of feminine activity on ovariectomized mice, the effects of estradiol, estradiol valerate and polyethylene glycol polymer compound of ethinyl estradiol on females The results showed that the estradiol, estradiol valerate and ethinyl estradiol were better than those of the parent compound in the amount of polyethylene glycol macromolecule compound Hormone activity is weak, the duration of the role of no extension.