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目的:分析武汉市汉阳区围生儿出生缺陷监测结果,为开展出生缺陷的预防、早期诊断和干预提供科学依据。方法:对武汉市汉阳区2008~2013年围生儿出生缺陷监测结果进行回顾性分析。结果:出生缺陷监测数为17 921例,出生缺陷数为166例,出生缺陷发生率为9.26‰。各年间出生缺陷率经趋势检验,无逐年上升趋势。前5位的出生缺陷类型分别是指(趾)畸形、外耳畸形、总唇裂、先天性心脏病、马蹄足内翻。指(趾)畸形连续4年成为发病率最高的畸形。产母年龄≥35岁,出生缺陷发生率明显增高,产母年龄与出生缺陷发生率差异有统计学意义(χ2=10.513,P<0.05)。结论:在重视三级预防和完善出生缺陷监测网络的基础上,加强武汉市汉阳区内协调机制,从产前-围产保健预防模式转变为孕前-围孕保健预防模式,降低出生缺陷发生率。
Objective: To analyze the monitoring results of birth defects of perinatal children in Hanyang District of Wuhan City, and provide a scientific basis for the prevention, early diagnosis and intervention of birth defects. Methods: A retrospective analysis was made on the surveillance of birth defects in Hanyang District from 2008 to 2013. Results: The number of birth defect monitoring was 17 921, the number of birth defects was 166 and the incidence of birth defects was 9.26 ‰. Birth defect rate in each year by the trend test, no year-on-year upward trend. The first five birth defects types are (toe) deformity, outer ear deformity, total cleft lip, congenital heart disease, clubfoot varus. Finger (toe) deformity became the highest incidence of deformity for 4 consecutive years. Maternal age ≥35 years old, the incidence of birth defects was significantly increased, maternal age and birth defects incidence difference was statistically significant (χ2 = 10.513, P <0.05). CONCLUSION: On the basis of attaching importance to tertiary prevention and improvement of birth defects monitoring network, the coordination mechanism in Hanyang District of Wuhan City should be strengthened to change from prenatal-perinatal care prevention mode to pre-pregnancy prevention prevention mode and to reduce the incidence of birth defects .