一、病例摘要: 1.先证者男,28岁,工人,未婚。3～4岁时,发热后面部出现少数淡褐色雀斑样斑点,15岁后逐年增多。夏季斑点颜色加深,呈暗褐色;日晒后斑点发红,有脱屑及灼痛。体检:发育、智力良好。面、颈、胸背上部,面前臂外侧及手部斑点密布,尤以面部为甚;斑点为黑褐色,深浅不一,呈弥漫性,伴有干燥、角化。前额及颊部还有几个米粒大小的暗红色 First, the case summary: 1 proband male, 28 years old, workers, unmarried. 3 to 4 years old, a few light brown freckles appear on the face after fever, increasing year after year. Summer dark spots color, dark brown; red spots after sun exposure, scaling and burning. Physical examination: development, good intelligence. Face, neck, upper chest, upper forearm and hand spots on the outside, especially in the face is even more; spot is dark brown, different shades, was diffuse, accompanied by dry, keratosis. There are several dark red cereal grains in the forehead and cheeks