低血钾软病在我县发现已有22年,本地称为“麻病”。病因可能与食用粗制棉籽油有关。1983年1月至1984年2月,本院又收治中、重型病例67例。我们注意到患者均有不同程度的代谢性酸中毒的表现,测 CO_2Cp多数偏低。入院时急查 CO_2Cp28例,其中20～39vol%的15例,40、49vol%的11例,50vol%以上的2例。但患者尿却多呈弱碱性,pH 值最高达8.8。一般说新鲜尿液应呈弱酸性反应。为避免本地有特殊性,我们做了对比观察,结果如下。低血钾软病组与其他两组有显著的差异(P<0.01)。一般认为,低血钾症常伴有碱中毒,血钾降低,肾小管细胞内缺钾,氢离子竞争性排泌增多,使尿酸化,故尿呈酸性,称“反常性酸性尿。低血钾软病则不同,多伴有酸中毒。本组又观察到尿多呈弱碱性,故认 Hypokalemia found in our county has 22 years, locally known as “disease.” Etiology may be related to the consumption of crude cottonseed oil. From January 1983 to February 1984, another 67 cases of medium and heavy cases were treated in our hospital. We note that patients have varying degrees of metabolic acidosis, the majority of measured CO_2Cp low. During admission, 28 cases of CO_2Cp were investigated urgently, among which 15 cases were 20 ~ 39vol%, 11 cases were 40,49vol% and 2 cases were more than 50vol%. However, patients were mostly alkaline urine, pH up to 8.8. In general, fresh urine should be weak acid reaction. In order to avoid local specialties, we made a comparative observation, the results are as follows. Hypokalemia soft-tissue group and the other two groups were significantly different (P <0.01). Is generally believed that hypokalemia is often accompanied by alkalosis, hypokalemia, tubular potassium deficiency, hydrogen ions increased competitive excretion, uric acid, so the urine was acidic, called "abnormal aciduria. Potassium is different, more accompanied by acidosis. This group also observed that urine mostly alkaline, so recognized