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酵母细胞的α因子对酵母产生和分泌外源多肽具有重要作用.α因子具有明显的促进细胞分泌作用.对这一系统的控制将有助于酵母表达和分泌外源蛋白.与抽提技术比较,细胞分泌具有多种优点,如促进多肽分泌,就能避免细胞内积聚潜在有害物质而损害细胞;亦不会产生选择压力,通过质粒丧失或发生重排而减低表达水平.分泌对于糖基化蛋白非常重要,因为糖酵解酶贯串于分泌过程.但还存在一些
The alpha factor in yeast cells plays an important role in the production and secretion of exogenous peptides by yeast.A factor has a significant role in promoting cell secretion.The control of this system will help yeast to express and secrete foreign proteins.Compared with the extraction technology , Cell secretion has many advantages, such as the promotion of peptide secretion, can avoid the accumulation of potentially harmful substances within the cell damage cells; also will not produce selective pressure, through the loss of plasmid or rearranged to reduce the expression level of secretion of glycosylation Proteins are important because glycolytic enzymes run through the secretory process, but there are still some