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目的:探讨输精管结扎与前列腺癌发病间的相关性。方法:以“输精管结扎术”、“前列腺癌”及其同义词和近义词为关键词,在CBMDisc、CMCC、CMAC、CNKI(1978年~2014年1月1日)和PubMed(1965年~2014年1月1日)等国内外数据库上进行全面检索,按文献纳入及剔除标准筛选出符合要求的文献,采用Meta分析方法进行综合分析。结果:共有17篇病例对照研究文献纳入本次研究,符合研究标准的研究对象33 841例,其中病例12 243例,对照21 598例。合并OR值(95%CI)为1.03(0.87,1.23)。结论:输精管结扎不增加前列腺癌的发病风险。
Objective: To investigate the correlation between vasectomy and the incidence of prostate cancer. Methods: The key words of “vasectomy”, “prostate cancer” and their synonyms and synonyms were analyzed in CBMDisc, CMCC, CMAC, CNKI (1978 ~ January 1, 2014) and PubMed ~ January 1, 2014) and other databases at home and abroad to conduct a comprehensive search, according to the inclusion of the literature and remove the standard screening of qualified documents, the use of Meta analysis of a comprehensive analysis. RESULTS: A total of 17 case-control study articles were included in this study. 33 841 subjects met the research criteria, of which 12 243 cases and 21 598 controls. The pooled OR (95% CI) was 1.03 (0.87, 1.23). Conclusion: Vasectomy does not increase the risk of prostate cancer.