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近20年,非甾体抗炎药的发展很迅速,其作用机理的研究也在进一步深化。非自体抗炎药的作用机制主要与花生四烯酸的代谢受抑有关。炎症的刺激使花生四烯酸(AA)从膜磷脂中释放,它在体内经历两种代谢途径,即环氧酶(CO)途径和脂氧酶(LO)途径,产生的所有代谢物都具有广泛
Nearly 20 years, the development of non-steroidal anti-inflammatory drugs is very rapid, and its mechanism of action is also further deepened. The mechanism of action of non-self-anti-inflammatory drugs and arachidonic acid metabolism mainly related. Inflammation triggers the release of arachidonic acid (AA) from membrane phospholipids, which undergo two metabolic pathways in vivo, the cyclooxygenase (CO) pathway and the lipoxygenase (LO) pathway, producing all metabolites that have widely