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评价国产新药抗痫灵（ＡＥＳ）对大鼠两种点燃模型的抗痫性。戊四唑（ＰＴＺ）点燃大鼠随机分４组（ｎ＝５），分别口服ＡＥＳｌ５０、３００、５００ｍｇ／ｋｇ／日或溶剂：杏仁核（ＡＭ）完全点燃大鼠随机分２组（ｎ＝５），分别口服ＡＥＳ５００ｍｇ／ｋｇ／日或溶剂。共维持４周。分别用ＰＴＺ或电流刺激测试其抗痫效果，每周一次。结果：ＡＥＳ对ＰＴＺ点燃有效，且呈剂量依赖性；ＡＥＳ对ＡＭ点燃全然无效。提示ＡＥＳ的抗痫性有惊厥发作类型的选择性，副作用小。
To evaluate the anti-epileptic effects of domestic anti-epileptic Ling (AES) on two kinds of ignition models in rats. The rats were randomly divided into 4 groups (n = 5), rats were randomly divided into 2 groups (n = 5), treated with oral administration of AES50, 300 and 500 mg / kg / day or solvent: amygdala (AM) ), Oral administration of AES500mg / kg / day or solvent. For a total of 4 weeks. Respectively with PTZ or current stimulation test its anti-epileptic effect, once a week. Results: AES was effective for PTZ ignition in a dose-dependent manner; AES was totally ineffective for AM ignition. Tip AES anti-epileptic seizures have the type of seizure, side effects.