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实验在乌拉坦麻醉大鼠上进行。观察了微量精氨加压素在外侧隔核的心血管作用，并从中枢和外周两方面探讨了其作用机理。结果发现：（１）外侧隔核注射精氨加压素（０．３ｇ／Ｌ），使平均动脉压和心率明显升高（分别为２４±０．２ｋＰａ和４５．０±３．５次／ｍｉｎ，均Ｐ＜０．０１）。（２）在侧脑室注射钠洛酮（２ｇ／Ｌ），使上述心血管效应降至１．２±０．１ｋＰａ和２０．５±２．０次／ｍｉｎ。在延髓头端腹外侧注射普鲁卡因（２０ｇ／Ｌ，则使上述效应降至０．２±０．１ｋＰａ和１２．０±２．０次／ｍｉｎ。（３）静脉注射心得安（０．３ｍｇ／ｋｇ），使上述升压效应降至１．７±０．８ｋＰａ，加快心率作用不再出现。实验表明：微量精氨加压素在外侧隔核可兴奋心血管活动。该作用主要是通过延髓头端腹外侧区，导致外周血管收缩、心率加快而实现，中枢阿片样物质参与了这一过程。
The experiment was performed on uratan anesthetized rats. The cardiovascular effects of microparticulate vasopressin on lateral septal nuclei were observed, and its mechanism of action was explored from both the central and peripheral aspects. The results showed that: (1) Injection of arginine vasopressin (0.3g / L) into lateral septal nucleus significantly increased mean arterial pressure and heart rate (24 ± 0.2kPa and 45.0 ± 3.5times / min, all P <0.01). (2) Sodium oxylorone (2g / L) was injected into the lateral ventricle to reduce the cardiovascular effects to 1.2 ± 0.1kPa and 20.5 ± 2.0 beats / min. In the rostral ventrolateral injection of procaine (20g / L, the above effect was reduced to 0.2 ± 0.1kPa and 12.0 ± 2.0 times / min. (3) intravenous propranolol (0 .3mg / kg), so that the step-up effect reduced to 1.7 ± 0.8kPa, to speed up the role of the heart rate no longer appear. Experiments show that: microparticulate vasopressin in the lateral septal excitement of cardiovascular activity. The role of the main Is through the rostral ventrolateral medulla, resulting in peripheral vasoconstriction, heart rate and achieve central opioid involved in this process.