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目的 探讨对精神分裂症患者在奥氮平治疗的基础上联合采用团体心理治疗干预对提高治疗效果以及改善患者社会功能的作用.方法 选择2018年1月～2020年12月收治的明确诊断的精神分裂症者计80例,以随机数表法作为分组方式将患者分为奥氮平治疗对照组(n=40)与联合使用团体心理治疗干预实验组(n=40),比较两组临床疗效,评价治疗前后阳性与阴性症状量表(PANSS)评分,并采用个人与社会功能量表(PSP)调查患者在治疗前后的社会功能.结果 实验组治疗总有效率95.00％,高于对照组75.00％,差异有统计学意义(P＜0.05,x2=6.275).治疗前两组PANSS在阳性因子、阴性因子、一般病理3个维度评分与PSP评分差异均无统计学意义(P＞0.05,t=0.478、0.742、1.313、0.234).治疗后实验组PANSS在阳性因子、阴性因子、一般病理3个维度的评分分别为14.12±1.08分、17.57±1.30分、32.10±1.22分,均小于对照组;PSP评分为68.91±10.65分,大于对照组,差异有统计学意义(P＜0.05,t=3.308、3.681、3.759、3.257).结论 对精神分裂症患者在奥氮平治疗的基础上联合团体心理治疗干预可提高临床疗效,有利于改善患者精神分裂症状,且可提高患者社会功能,值得推广.“,”Objective To explore the effect of group psychotherapy intervention on improving the therapeutic effect and social function of patients with schizophrenia on the basis of olanzapine therapy. Methods Eighty patients with schizophrenia with definite diagnosis were selected, and the time of case collection and data collection was from January 2018 to December 2020. They were randomly divided into Olanzapine treatment control group (n=40) and combined group psychotherapy intervention group (n=40). The clinical efficacy of the two groups was compared, and the positive and negative symptom scale (PANSS) scores before and after treatment were evaluated. The personal and social functioning scale (PSP) was used to investigate the social functioning of the patients before and after treatment. Results The total effective rates of the experimental group and the control group were 95.00％ and 75.00％ (P＜0.05, x2=6.275). Before treatment, there was no statistical significance in the three dimensions of positive factor, negative factor, general pathology score and PSP score between the two groups (P＞0.05, t=0.478, 0.742, 1.313, 0.234). After treatment, the scores of positive factor, negative factor and general pathology of PANSS in experimental group were 14.12±1.08, 17.57±1.30 and 32.10±1.22 points respectively, which were all lower than those in control group. The PSP score was 68.91±10.65, which was higher than that of the control group (P＜0.05, t=3.308, 3.681, 3.759, 3.257). Conclusion Based on olanzapine treatment combined with group psychotherapy intervention for schizophrenia patients can improve the clinical efficacy, improve the symptoms of schizophrenia patients, and improve the social function of patients, worthy of promotion.