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目的：观察缺氧预处理对家兔血管平滑肌细胞缺氧－复氧损伤的影响。方法：采用血管平滑肌细胞缺氧－复氧模型，用短暂缺氧进行预处理。结果：缺氧预处理能提高缺氧－复氧后血管平滑肌细胞存活率（ｐ＜０．０１）、减少细胞丙二醛产生（Ｐ＜０．０１）及乳酸脱氢酶的漏出（Ｐ＜０．０１）。结论：离体血管平滑肌细胞存在着预处理保护现象。
Objective: To observe the effect of hypoxia preconditioning on hypoxia-reoxygenation injury of vascular smooth muscle cells in rabbits. Methods: The hypoxia - reoxygenation model of vascular smooth muscle cells was used to pretreat with hypoxia. Results: Hypoxic preconditioning increased the survival rate of vascular smooth muscle cells (P <0.01) and decreased the malondialdehyde (MDA) production (P <0.01) and lactate dehydrogenase (P < 0.01). Conclusion: Pre-treatment protection exists in isolated vascular smooth muscle cells.