目前在东南亚有1亿人口居住在抗氯喹株恶性疟流行区内,加之媒介对杀虫剂的抗性,严重阻碍着抗疟措施的顺利完成。60年代仅局限于泰国、南越和马来西亚的个别地区,70年代以惊人的速度扩散,成了东南亚抗疟失败的主要因素。氯喹抗性的体内测定法,缺点之一是受机体免疫状态的影响较大,其二是需时7天 At present, 100 million people in Southeast Asia live in the endemic area of ​​chloroquine-resistant falciparum malaria, and the resistance of the media to insecticides seriously hinders the smooth completion of the anti-malaria measures. The 1960s were confined to some areas of Thailand, South Vietnam and Malaysia. The proliferation of the 1970s at an alarming rate became the main factor in the failure of anti-malaria in Southeast Asia. Chloroquine resistance in vivo assay, one of the drawbacks is affected by the immune status of the larger, the second is the need for 7 days