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目的总结用精制破伤风抗毒素 ( TAT)治疗新生儿破伤风经验。方法采用静脉、鞘内、脐周封闭 3种途径同时应用 ,总剂量 1~3万 U。结果较单独途径给药疗效好 ,病死率由 40 %降至 16 %。结论 3种途径同时 1次给药是一种最佳疗法。
Objective To summarize the experience of neonatal tetanus with refined tetanus antitoxin (TAT). Methods intravenous, intrathecal, umbilical closed three ways simultaneously with a total dose of 1 to 30,000 U. The results were better than the single route of administration, mortality decreased from 40% to 16%. Conclusion The three routes of simultaneous administration are the best therapy.