Pierre Druilhe和Jean-Louis Perignon在最近发表的一篇文章中,论述了慢性恶性疟原虫感染是如何在部分有免疫力的个体中持续存在的。他们认为,此类感染由一种由单核细胞介导、抗体依赖性的裂殖子自身触发机制操纵的。本文作者认为,不论他们所提出的这一机制是否详实、准确,他们所指出的针对无性期虫体的自然免疫,不仅对降低原虫感染密度非常有效,而且具有部分有效抗虫 In a recent article by Pierre Druilhe and Jean-Louis Perignon, how chronic P. falciparum infection persists in partially immunized individuals is discussed. They believe that such infections are manipulated by a monocyte-mediated, antibody-dependent merozoite self-triggering mechanism. The authors believe that their natural immunity against asexual parasites, irrespective of their detailed and accurate mechanisms, is not only very effective in reducing the density of protozoa, but also has some effective resistance to insects