系统红斑狼疮可有口、鼻、咽部等处粘膜溃疡的表现,但因鼻粘膜溃疡而致鼻中隔穿孔者极为少见。迄今,只有 Alcala 等报道的3例及国内唐令铨等最近报道的1例(中华内科杂志,20:5,1981)。我院最近亦见到1例,现报告如下:符××,女性,34岁。住院号0106。因反复浮肿,时有双膝关节酸痛三年,一周来纳差、乏力,精神萎糜,出现浮肿,三天来症状加重,气促,尿少,并有低热,查尿常 Systemic lupus erythematosus can have mouth, nose, throat and other mucosal ulcers at the performance, but due to nasal ulcer nasal septum perforation who is extremely rare. To date, only three cases reported by Alcala et al. And one recently reported by domestic Tang Ling et al. (Chinese Journal of Internal Medicine 20: 5,1981). Our hospital also recently saw 1 case, the report is as follows: Fu × ×, female, 34 years old. Hospital number 0106. Due to repeated edema, sometimes double knee pain for three years, a week to anorexia, fatigue, spiritual wilt, edema, three days to symptoms, shortness of breath, oliguria, and fever, check urine