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我院于1978年,收治3例食物中毒患者,其中2例静脉滴注强力霉素时出现癫痫样发作。例1 范某,女,20岁。于1978年7月22日中午吃臭肉一小碗,次日展开始发热,头痛,恶心,呕吐,腹痛、腹泻,解水样便数次,于当日入院。体检:体温39℃,呼吸30次/分,脉搏120次/分。血压100/70毫米汞柱。心肺正常。腹软,肝脾未扪及,肠鸣亢进,血常规正常,大便常规:白细胞(++),红细胞(+),诊断:细菌性食物中毒。给予强力霉素0.4克,维生素C1.5克,加入任氏液1,000毫升中,滴速为60滴/分。20分钟后,患者突然双眼上翻,四肢抽动,口吐白沫,二便失禁。呼吸及脉搏加快,瞳孔散大,对光反射消失。
Our hospital in 1978, admitted to 3 cases of food poisoning patients, including 2 cases of intravenous infusion of doxycycline appear epileptic seizures. Example 1 fan, female, 20 years old. On July 22, 1978, a small bowl of smelly meat was eaten at the noon of July 22, 1978 and the next day, fever, headache, nausea, vomiting, abdominal pain, diarrhea and dehydration were started several times and admitted to the hospital on the same day. Physical examination: body temperature 39 ℃, breathing 30 beats / min, pulse 120 beats / min. Blood pressure 100/70 mm Hg. Cardiopulmonary normal. Abdominal soft, liver and spleen not palpable, bowel hyperactivity, normal blood, stool routine: white blood cells (+ +), red blood cells (+), diagnosis: bacterial food poisoning. To give doxycycline 0.4 grams, vitamin C1.5 grams, adding Ren Ren 1,000 ml in, drip rate of 60 drops / min. Twenty minutes later, the patient suddenly doubled his eyes and twitched his limbs, foaming at his mouth and incontinence two times. Breathing and pulse speeding, mydriasis, light reflex disappeared.