目的:探讨子宫腺肌病与子宫肌瘤的临床特点及实验室检查,提高对子宫腺肌病术前确诊率。方法:选择52例子宫腺肌病患者和63例子宫肌瘤患者为研究对象,并对临床症状、妇科检查、B超结果及血清CA125水平进行比较。结果:两组患者发病年龄和临床症状相近,但子宫腺肌病的痛经症状明显(P<0.01);妇科检查子宫腺肌病的子宫常均匀性增大,且一般增大<12孕周,而宫体压痛明显高于子宫肌瘤(P<0.01);两组B超诊断符合率分别为59.6%和91.2%,有显著差异(P<0.05);子宫腺肌病组血清CA125阳性率79.8%,子宫肌瘤组血清CA125阳性率4.1%,有显著差异(P<0.01)结论:综合分析子宫腺肌病与子宫肌瘤的临床表现、妇科检查、B超所见和血清CA125水平有助于提高子宫腺肌病的术前诊断。 Objective: To investigate the clinical features and laboratory tests of adenomyosis and uterine fibroids and to improve the preoperative diagnosis of adenomyosis. Methods: Fifty-two patients with adenomyosis and 63 patients with uterine fibroids were selected as study subjects. Clinical symptoms, gynecological examination, B-ultrasound results and serum CA125 levels were compared. Results: The onset age and clinical symptoms of both groups were similar, but the symptoms of dysmenorrhea in adenomyosis were obvious (P <0.01). The uterine regularity of adenomyosis in gynecological examination increased and generally increased by <12 gestational weeks, (P <0.01). The coincidence rates of B-mode ultrasound and B-mode ultrasonography were 59.6% and 91.2% respectively (P <0.05). The positive rate of serum CA125 in adenomyosis was 79.8% %, The positive rate of serum CA125 in uterine fibroids group was 4.1% (P <0.01). Conclusion: The clinical manifestations of gynecological adenomyosis and uterine fibroids were analyzed comprehensively. The results of gynecological examination, B ultrasound and serum CA125 level were helpful To improve the preoperative diagnosis of adenomyosis.